Author

Marlea O’Brien

University of Iowa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 1 Assay:GWAS summary statistics· 1 Organism:human· 1 Approach:mixed model· 1 Organism:multiple species· 1 Research Focus:phylogenetics / evolution· 1 Research Focus:polygenic risk· 1 Assay:scATAC-seq· 1

Frequent Co-Authors

Allison M. MomanyiD· 1 shared Dabney Hofammann· 1 shared J. Bruce TombliniD· 1 shared Jacob J. MichaelsoniD· 1 shared Jeffrey Clark MurrayiD· 1 shared Jin‐Young KohiD· 1 shared Lucas G. CasteniD· 1 shared Savantha Thenuwara· 1 shared

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2026-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperEvolutionary Biology

Allison M. MomanyORCID

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1 paper

Recent·Most cited

Ancient regulatory evolution shapes individual language abilities in present-day humans

Lucas G. Casten, Tanner Koomar, Taylor Thomas, Jin‐Young Koh, Dabney Hofammann, Savantha Thenuwara, Allison M. Momany, Marlea O’Brien, Jeffrey Clark Murray, J. Bruce Tomblin, Jacob J. Michaelson

Polygenic score variants in HAQERs (Human Ancestor Quickly Evolved Regions, <0.1% of the genome) predict spoken language but not nonverbal IQ; language associations replicate in SPARK, ABCD and UK Biobank.

Science Advances · Apr 22, 2026Peer-reviewedEvolutionary Biology✦ In-depth digest