Upregulation of Genetic Markers of Poor Prognosis following Chemotherapy in Acute Myeloid Leukemia Cells
Andrew Taylor, Michael K. Strasser, Marlee Ng, Irit Rubin, Arja Kaipainen, Angela Oliveira Pisco, Sui Huang
The paper shows that chemotherapy upregulates genes linked to poor prognosis in surviving leukemia cells, suggesting treatment may increase malignancy rather than reduce it.
bioRxiv · Feb 15, 2026 · PreprintCancer Biology