Systematic evaluation of cell-type deconvolution pipelines for sequencing-based bulk DNA methylomes
Yunhee Jeong, Lisa Barros de Andrade e Sousa, Dominik Thalmeier, Réka Tóth, Marlene Ganslmeier, Kersten Breuer, Christoph Plass, Pavlo Lutsik
This study benchmarks six sequencing-based and two array-based cell-type deconvolution methods for bulk DNA methylomes, identifying the best-performing method and factors affecting performance.
Briefings in Bioinformatics · Jul 6, 2022Peer-reviewedBioinformatics