Using reference-free compressed data structures to analyse sequencing reads from thousands of human genomes
Dirk-Dominic Dolle, Zhicheng Liu, Matthew L Cotten, Jared T Simpson, Zamin Iqbal, Richard Durbin, Shane McCarthy, Thomas Keane
This paper introduces a population BWT data structure to efficiently store and analyze sequencing reads from thousands of human genomes, enabling variant calling and viral detection.
bioRxiv · Jun 22, 2016Genomics