Md Rafsan Jani

PMPNN-DDG: an accurate machine learning-based {triangleup}{triangleup}G prediction pipeline trained on a novel interpretable feature set extracted from ProteinMPNN

PMPNN-DDG is a Random Forest model predicting single-point mutation-induced protein stability changes using features from ProteinMPNN, achieving high accuracy on independent test sets.

Cluster Analysis for Protein Sequences

The paper compares MMseqs2 clustering methods with traditional ML algorithms on protein sequences and finds MMseqs2 methods significantly outperform.