Genotype-Dependent Dysregulation of the MDM2-p53 Axis and Breast Cancer Susceptibility in Bangladeshi Women: A Cas-Control Study
Mahim Hassan Chowdhury, Farzana Islam, Adiba Ayesha Khan, Md. Ayman Siddique, Nushaiba Binte Hasan, Mahinul Islam Samrat, Mehrin Haque Tanisha, Jarin Tasnim, Samiha Mahjabin, Md. Nazmul Islam, Md. Aminul Haque
This study identifies a genotype-specific association between MDM2 rs2279744 polymorphism and breast cancer risk in Bangladeshi women, showing increased risk for TG genotype and protective effect for GG genotype.
bioRxiv · May 21, 2026 · PreprintCancer Biology