Multi-scale machine learning model predicts muscle and functional disease progression in FSHD
Silvia S. Blemker, Lara Riem, Olivia DuCharme, Megan Pinette, Kathryn Eve Costanzo, Emma Weatherley, Jeffrey M. Statland, Stephen J. Tapscott, Leo H. Wang, Dennis Shaw, The Move+ Investigator Team, Xing Song, Doris G. Leung, Seth D. Friedman
This paper develops a multi-scale machine learning model to predict muscle and functional disease progression in FSHD using MRI and clinical data, achieving strong predictive performance in holdout datasets.
Scientific Reports · Jul 16, 2025Peer-reviewedBioengineering