Accelerating Antibody Development: Sequence and Structure-Based Models for Predicting Developability Properties through Size Exclusion Chromatography
A N M Nafiz Abeer, Mehdi Boroumand, Isabelle Sermadiras, Jenna G Caldwell, Valentin Stanev, Neil Mody, Gilad Kaplan, James Savery, Rebecca Croasdale-Wood, Maryam Pouryahya
This study compares sequence and structure-based models for predicting antibody developability properties using SEC assays, identifying the most effective in silico approach.
bioRxiv · Feb 2, 2025 · PreprintBioinformatics