Author

Meng Yuan

Southwest Medical University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Bioinformatics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:mechanistic / dynamical model· 1 Assay:protein sequence· 1 Assay:proteomics· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Athanasios V. Vasilakos· 1 shared Jian WangiD· 1 shared Jiaxin Zhan· 1 shared Jun LongiD· 1 shared Mingqing WangiD· 1 shared Wanying XieiD· 1 shared Xingchun WangiD· 1 shared Xingxia WangiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBioinformatics

Athanasios V. Vasilakos

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2 papers

Recent·Most cited

Improving Variant Effect Prediction by Steering Sparse Mechanistic Features in Protein Language Models

Mingqing Wang, Meng Yuan, Athanasios V. Vasilakos, Yonghong He, Zhixiang Ren

This paper improves variant effect prediction by modifying protein language models with sparse mechanistic features, achieving significant performance gains across multiple datasets.

bioRxiv · May 15, 2026 · PreprintBioinformatics

Hedyotis Diffusae Herba Mitigates Rotenone-Induced Neurotoxicity via Akt Pathway in SH-SY5Y Cells

Jian Wang, Yisong Liu, Ying Fan, Meng Yuan, Wanying Xie, Xingchun Wang, Yi Zhong, Jiaxin Zhan, Xinyao Huang, Yibo Zhang, Jun Long, Xingxia Wang

This study identifies HDH's neuroprotective effects against rotenone toxicity in SH-SY5Y cells via Akt pathway activation and anti-inflammatory/antioxidant mechanisms.

bioRxiv · Aug 3, 2025 · PreprintCell Biology