Telmisartan alters the transcriptomes of cancer associated fibroblasts and fibrocytes in a solid tumour model
Che-Min Lee, Nikita Telkar, Brennan J. Wadsworth, Rachel A. Cederberg, Rocky Shi, Lisa Zhan, Prabhreet Sekhon, Meredith A. Clark, Michael GS Hall, Kiersten N. Thomas, Wan L. Lam, Kevin L. Bennewith
This study shows telmisartan alters CAF transcriptomes in solid tumours, reducing collagen and fibrosis without eliminating CAFs.
bioRxiv · Sep 18, 2026 · PreprintCancer Biology