Gene Expression Signatures of Sporadic ALS Motor Neuron Populations
Ranjan Batra, Kasey Hutt, Anthony Vu, Stuart J Rabin, Michael W Baughn, Ryan T Libby, Shawn Hoon, John Ravits, Gene W Yeo
The paper identifies gene expression signatures in sporadic ALS motor neurons using RNA-seq and validates them with qPCR, revealing defects in neurotransmitter biosynthesis and RNA-processing pathways.
bioRxiv · Feb 3, 2016 · PreprintNeuroscience