Inferring intracellular signal transduction circuitry from molecular perturbation experiments
Michelle L. Wynn, Megan E. Egbert, Nikita Consul, Jungsoo Chang, Zhi-Fen Wu, Sofia D. Meravjer, Santiago D. Schnell
This paper introduces a logic-based network inference method to predict intracellular signaling circuits from perturbation experiments, validated on EGF receptor signaling in breast epithelial cells.
Bulletin of Mathematical Biology · Apr 28, 2017Peer-reviewedSystems Biology