Spatial transcriptomics reveals distinct inflammatory and adaptive immune properties of rheumatoid arthritis synovial fibroblasts
Camilla Ribeiro Lima Machado, Mina Yao, David L. Boyle, Robert J. Benschop, James T. Parker, Wei Wang, Gary S. Firestein
This study uses spatial transcriptomics to identify distinct gene expression patterns in RA synovial fibroblasts and macrophages, revealing region- and cell-type-specific roles in inflammation and adaptive immunity.
bioRxiv · Nov 8, 2025 · PreprintImmunology