Spatially resolved mapping of cells associated with human complex traits
Liyang Song, Wenhao Chen, Junren Hou, Minmin Guo, Jian Yang
The paper introduces gsMap, a method that maps disease-relevant cells to human complex traits using spatial transcriptomics and GWAS data, revealing spatial patterns of schizophrenia and depression-associated glutamatergic neurons.
Nature · Mar 19, 2025Peer-reviewedGenetic & Genomic Medicine