A meta-analysis of genetic variant pathogenicity and sex differences in UBQLN2-linked amyotrophic lateral sclerosis and frontotemporal dementia
Kyrah M. Thumbadoo, Laura R. Nementzik, Molly E.V. Swanson, Birger Victor Dieriks, Michael Dragunow, Richard L. M. Faull, Maurice A. Curtis, Ian P. Blair, Garth A. Nicholson, Kelly L. Williams, Emma L. Scotter
This paper performs a meta-analysis of UBQLN2 genetic variants in ALS/FTD, finding sex-specific differences in age at onset and aggregate burden in brain tissue.
medRxiv · Oct 25, 2024 · PreprintGenetic & Genomic Medicine