Efficient ageing: Simulated lesion of the structural connectome reveals optimised decline in the healthy ageing brain
Nikita Kudriavtsev, Mattia Rosso, Gemma Fernández‐Rubio, Elisa Serra, Morten L Kringelbach, Peter Vuust, Leonardo Bonetti
The paper simulates lesions in age-sensitive white-matter regions to show that healthy ageing involves a selective reconfiguration of structural connectivity rather than uniform decline.
bioRxiv · Jun 2, 2026 · PreprintNeuroscience