Synapses, predictions, and prediction errors: a neocortical computational study of MDD using the temporal memory algorithm of HTM.
Mohamed A. Sherif, Mostafa Khalil, Rammohan Shukla, Joshua C. Brown, Linda L. Carpenter
This study uses a temporal memory algorithm to model how synaptic atrophy in the neocortex affects predictive capacity and prediction confidence, linking it to major depressive disorder symptoms.
Frontiers in Psychiatry · Feb 23, 2023Peer-reviewedNeuroscience