OpenFold: Retraining AlphaFold2 yields new insights into its learning mechanisms and capacity for generalization
Gustaf Ahdritz, Nazim Bouatta, Christina Floristean, Sachin Kadyan, Qinghui Xia, William Gerecke, Timothy J. O’Donnell, Daniel Berenberg, I. Fisk, Niccolò Zanichelli, Bo Zhang, Arkadiusz Nowaczynski, Bei Wang, Marta M. Stepniewska-Dziubinska, Shang Zhang, , Mohammed AlQuraishi
The paper trains a new version of AlphaFold2, OpenFold, and evaluates its generalization ability and learning mechanisms.
Nature Methods · May 14, 2024Peer-reviewedBioinformatics