Odorant receptor inhibition is fundamental to odor encoding
Patrick Pfister, Benjamin C. Smith, Barry J. Evans, Jessica H. Brann, Casey Trimmer, Mushhood Sheikh, Randy Arroyave, Gautam Reddy, Hyo-Young Jeong, Daniel A. Raps, Zita A. Peterlin, Massimo Vergassola, Matthew Edward Rogers
The paper investigates how odorant receptor inhibition shapes neuronal responses to complex odors and finds that OR antagonism, inverse agonism, and partial agonism are common and combinatorial in olfactory sensory neurons.
Current Biology · Jan 1, 2019Peer-reviewedNeuroscience