Partially-functional exhausted CD8+ T cells can contribute to short-term viral suppression: a computational prediction for children with perinatal HIV
Alexis Hoerter, Alexa Petrucciani, Fatma Marshed, Mussa Mwamzuka, Aabid Abdulmajid Ahmed, Alka Khaitan, Elsje Pienaar
The paper uses a computational model to predict how T cell exhaustion affects viral control in children with perinatal HIV, finding that exhausted CD8+ T cells can contribute to short-term viral suppression.
bioRxiv · Sep 18, 2025 · PreprintSystems Biology