Periplasmic stress contributes to a tradeoff between protein secretion and cell growth in E. Coli Nissile
Sitaram M. Emani, Anton Kan, T Storms, S Bonanno, J Law, Sanhita Ray, N Joshi
The paper identifies a tradeoff between cell growth and protein secretion in E. coli Nissile, showing that high secretion leads to periplasmic stress and reduced growth.
bioRxiv · Jan 9, 2023 · PreprintSynthetic Biology