Metabolic dysregulation induces impaired lymphocyte memory formation during severe SARS-CoV-2 infection
H. Nguyen, S. Gurshaney, A. M. Alvarez, K. Ezhakunnel, A. Manalo, T.-H. Huynh, N. -T. Le, D. Lupu, S. Gardell
This study investigates how metabolic dysregulation during severe SARS-CoV-2 infection impairs lymphocyte memory formation through hypoxia-induced metabolic shifts and cellular exhaustion.
bioRxiv · Dec 6, 2021 · PreprintImmunology