Healthy human induced pluripotent stem cell-derived cardiomyocytes exhibit sex dimorphism even without the addition of hormones
S. E. Givens, A. A. Andebrhan, E. G. Schmuck, A. Renaud, J. E. Abrahante-Llorens, N. Stanis, J. R. Dutton, B. M. Ogle
The paper generates hiPSC-CM from male and female donors and finds sex dimorphism in calcium handling and gene expression without hormone exposure.
bioRxiv · May 29, 2024Cell Biology