Understanding the role of IQ motif-containing GTPase-activating protein 1 as a potential disruptor of the essential adhesion module at cell-cell junctions
This study investigates how IQGAP1 disrupts the β-catenin/α-catenin complex through mechanical detachment and electrostatic interactions using simulations and mutagenesis.
bioRxiv · Oct 26, 2026 · PreprintBiophysics