Identification and characterization of vasoactive intestinal peptide receptor antagonists with high-affinity and potent anti-leukemia activity
Yuou Wang, Anish Sen-Majumdar, Jian-Ming Li, Srijon Sarkar, Tenzin Passang, Sonia Mecorapaj, Swapnaa Balaji, Tenzin Kalsang, Antonio Ward, Yiwen Li, J. Cohen, Z. J. Chen, Kiranj Kishor Chaudagar, Pankoj Kumar Das, Shuhua Wang, , Edmund K. Waller
The paper identifies and characterizes VIP-R antagonists with high-affinity and potent anti-leukemia activity through in silico screening, in vitro testing, and in vivo validation.
Journal of Biological Chemistry · Dec 31, 2025Peer-reviewedImmunology