Tissue-specificity of gene expression diverges slowly between orthologs, and rapidly between paralogs
Nadezda Kryuchkova-Mostacci, Marc Robinson-Rechavi
The paper shows orthologs conserve tissue-specificity across species, while paralogs diverge rapidly, supporting a model where duplication leads to new functions through expression divergence.
PLOS Computational Biology · Dec 28, 2016Peer-reviewedEvolutionary Biology