Exploratory analysis and error modeling of a sequencing technology
Michael Inouye, Kerrin S. Small, Yik Y. Teo, Heng Li, Nava Whiteford, Tom Skelly, Irina Abnizova, Daniel J. Turner, Panos Deloukas, Dominic P. Kwiatkowski, Clive G. Brown, Taane G. Clark
The paper analyzes sequencing errors in Illumina Genome Analyzer data using logistic and log-linear models, improving error detection sensitivity and specificity by 3%.
bioRxiv · Mar 13, 2016 · PreprintGenomics