Small serine recombinases are markers for antiphage defense system discovery
Shelby E. Andersen, Joshua M. Kirsch, Navtej Singh, S Garrett, John C. C. Whitney, Jay R. Hesselberth, Breck A. Duerkop
The paper develops a bioinformatic pipeline using small serine recombinases to identify antiphage defense systems in bacterial genomes and metagenomes, finding they are genetically linked to these systems.
PLoS Biology · Aug 31, 2026Peer-reviewedMicrobiology