Balancing sensitivity and specificity in distinguishing TCR groups by CDR sequence similarity
Neerja Thakkar, Chris Bailey‐Kellogg
The paper evaluates how CDR3 sequence similarity can balance sensitivity and specificity in distinguishing TCR groups, showing it effectively classifies repertoires by antigen specificity and pathology.
BMC Bioinformatics · May 15, 2019Peer-reviewedBioinformatics