Mitochondrial DNA Variations Modulate Alveolar Epithelial Mitochondrial Function and Oxidative Stress in Newborn Mice Exposed to Hyperoxia
Jegen Kandasamy, Rui Li, Bianca M. Vamesu, Nelida C. Olave, Brian Halloran, Tamás Jilling, Scott W. Ballinger, Namasivayam Ambalavanan
This study shows that mtDNA variations affect mitochondrial function and oxidative stress in newborn mice exposed to hyperoxia, with implications for BPD risk in human infants.
bioRxiv · May 17, 2023 · PreprintDevelopmental Biology