Novel sex-biased outcomes in neuroblastoma are associated with distinct gene expression and chromosomal loss patterns.
Vishwa Patel, Mariya Raleigh, Lorraine-Rana E. Benhamou, Xin Shen, Erika C. Espinosa, Niharika R. Badi, Dennis A. Sheeter, John T. Powers
The paper identifies sex-biased outcomes in neuroblastoma, showing female patients with MYCN non-amplified high-risk disease have worse survival than males, linked to H19/DLK1 expression and chromosome 11q retention.
bioRxiv · Jun 14, 2024 · PreprintCancer Biology