Sex-Specific Pathophysiological Signatures in Allometric Dosing-Controlled Bleomycin Acute Lung Injury Model
Samuel Gillman, Alice Ngu, Michael Lush, Nikolay Karpuk, Kevin M. Hu, Steven J. Lisco, Hanjun Wang
This study shows that body-weight-matched bleomycin-induced ALI in rats reveals sex-specific pathophysiological differences, with males showing worse hypoxemia and distinct molecular responses compared to females.
bioRxiv · Mar 12, 2026 · PreprintPhysiology