GenomicsSciencePeer-reviewed
A single cell multi-omic analysis identifies molecular and gene-regulatory mechanisms dysregulated in the developing Down syndrome neocortex
Celine K. Vuong, Alexis Weber, Patrick Seong…·Luis de la Torre-Ubieta
This study uses single-nucleus multi-omics to analyze the developing Down syndrome neocortex, identifying dysregulated molecular and gene-regulatory mechanisms affecting neurogenesis and cell specification.