The effect of DNA methylation on DNA structure and DNA-small molecule interactions
Gözdem Çavdar, Nurdan Emin, Aybüke Gülkaya, Deniz Irem Alpinanc, Antoine Marion, Özgül Persil Çetinkol
This study investigates how DNA methylation affects DNA structure and small molecule interactions, showing increased stability in fully methylated DNA and specific hydrophobic interactions with drugs like Dox.
bioRxiv · Jul 30, 2026 · PreprintBiochemistry