GLnexus: joint variant calling for large cohort sequencing
Michael F. Lin, Ohad Rodeh, John Penn, Xiaodong Bai, Jeffrey G. Reid, Olga A. Krasheninina, William J. Salerno
GLnexus, a joint variant caller backed by an incrementally growable gVCF database, largely matched GATK on 50,000 exomes while keeping more rare indels and using 3.8–6.6-fold fewer core-hours.
bioRxiv · Jun 11, 2018 · PreprintBioinformatics✦ In-depth digest