The E2F1 regulon orchestrates a proliferative emergency and vascular programming in fetal endothelial progenitors exposed to GDM: a sex-stratified systems medicine approach
Muyiwa Seyi Adegbaju, Oluseyi Babayeju, Olanrewaju B. Morenikeji, Olusola Daniel Ojurongbe, Bolaji N. Thomas
The paper identifies the E2F1 regulon as a driver of sex-specific vascular programming in fetal endothelial progenitors exposed to GDM, revealing a proliferative emergency in females.
bioRxiv · Jul 1, 2026 · PreprintGenomics