Genetic variants in the SHISA6 gene are associated with delayed cognitive impairment in two family datasets
Jairo D. Ramos, Laura J. Caywood, Michael B. Prough, Jason E. Clouse, Sharlene D. Herington, Susan H. Slifer, M. Denise Fuzzell, Sarada L. Fuzzell, Sherri D. Hochstetler, Kristy L. S. Miskimen, Leighanne R. Main, Michael D. Osterman, Owen Laframboise, Andrew F. Zaman, Patrice L. Whitehead, , William K. Scott
The paper identifies three SNVs associated with delayed age at onset of cognitive impairment in Amish populations, with one replicated in an independent dataset and linked to the SHISA6 gene.
Alzheimer s & Dementia · May 1, 2022Peer-reviewedGenetic & Genomic Medicine