Author

P. Barrat-Charlaix

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Organism:human· 1 Research Focus:protein design· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

C. Stocker· 1 shared D. Hilvert· 1 shared J. Huddleston· 1 shared M. Figliuzzi· 1 shared M. Socolich· 1 shared M. Weigt· 1 shared P. Kast· 1 shared R. Monasson· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBiochemistry

C. Stocker

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2 papers

Recent·Most cited

Limited predictability of amino acid substitutions in seasonal influenza viruses

P. Barrat-Charlaix, J. Huddleston, T. Bedford, R. Neher

This study assesses the predictability of amino acid substitutions in seasonal influenza viruses and finds that current frequency is the strongest predictor of fixation, while other features like epitope occurrence or LBI have limited predictive power.

bioRxiv · Jul 31, 2020Evolutionary Biology

Evolution-based design of chorismate mutase enzymes

W. P. Russ, M. Figliuzzi, C. Stocker, P. Barrat-Charlaix, M. Socolich, P. Kast, D. Hilvert, R. Monasson, S. Cocco, M. Weigt, R. Ranganathan

This paper demonstrates an evolution-based design process for synthetic enzymes using sequence data, showing that statistical models can generate functional sequences with substantial diversity.

bioRxiv · Apr 1, 2020 · PreprintBiochemistry