Does alpha-tocopherol flip-flop help to protect membranes against oxidation?
P. Boonnoy, M. Karttunen, J. Wong-ekkabut
This study uses molecular dynamics simulations to show that alpha-tocopherol flip-flop rates increase in oxidized lipid bilayers, reducing free energy barriers and enhancing membrane protection against oxidation.
bioRxiv · Sep 19, 2018Biophysics