Hippo pathway effectors YAP1/TAZ induce a EWS-FLI1-opposing gene signature and associate with disease progression in Ewing Sarcoma
P. Rodriguez-Nunez, L. Romero-Perez, A. T. Amaral, P. Puerto-Camacho, C. Jordan, T. Grunewald, D. Marcilla, E. de Alava, J. Diaz-Martin
The paper shows YAP1/TAZ promote disease progression in Ewing Sarcoma by opposing the EWS-FLI1 fusion protein's transcriptional effects.
bioRxiv · Mar 27, 2019Cancer Biology