A profile-based method for identifying functional divergence of orthologous genes in bacterial genomes
Nicole E Wheeler, Lars Barquist, Robert A Kingsley, Paul P Gardner
The paper introduces a hidden Markov model-based method, delta-bitscore, to identify functional divergence in orthologous genes and applies it to study host adaptation in Salmonella enterica.
Bioinformatics · Aug 8, 2016Peer-reviewedBioinformatics