Author

Peter Krusche

Primary ORCID profile (0009-0003-2541-5181 · 5 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Peter KruscheiD5 papers · Illumina (United Kingdom)

Biology Disciplines

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Bioinformatics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Organism:bacteria (other)· 1 Organism:human· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Aaron L Halpern· 1 shared Benjamin L Moore· 1 shared Dan J Woodcock· 1 shared David R Bentley· 1 shared Elliott H Margulies· 1 shared Epameinondas Fritzilas· 1 shared Frederick M Cohan· 1 shared Gil McVeaniD· 1 shared

Activity by Year

2016-2016 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBioinformatics

Aaron L Halpern

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2 papers

Recent·Most cited

Genomic plasticity and rapid host switching promote the evolution of generalism in the zoonotic pathogen Campylobacter

Dan J Woodcock, Peter Krusche, Norval JC Strachan, Ken J Forbes, Frederick M Cohan, Guillaume Meric, Samuel K Sheppard

This study models how horizontal gene transfer and recombination influence the evolution of host generalism in Campylobacter, showing that low recombination increases standing variation for adaptive responses.

bioRxiv · Oct 10, 2016Microbiology

A reference dataset of 5.4 million phased human variants validated by genetic inheritance from sequencing a three-generation 17-member pedigree

Michael A Eberle, Epameinondas Fritzilas, Peter Krusche, Morten Kallberg, Benjamin L Moore, Mitchell A Bekritsky, Zamin Iqbal, Han-Yu Chuang, Sean J Humphray, Aaron L Halpern, Semyon Kruglyak, Elliott H Margulies, Gil McVean, David R Bentley

The paper generates a high-confidence variant catalogue from whole-genome sequencing of a three-generation pedigree, validated by haplotype transmission and showing improved accuracy over existing benchmarks.

bioRxiv · Aug 2, 2016Bioinformatics