A fast and efficient colocalization algorithm for identifying shared genetic risk factors across multiple traits
Christopher N. Foley, James R Staley, Philip G. Breen, Benjamin B. Sun, Paul Kirk, Stephen Burgess, Joanna M. M. Howson
This paper introduces HyPrColoc, a Bayesian algorithm for multi-trait colocalization using GWAS summary statistics, identifying 43 regions where coronary heart disease colocalizes with other traits.
Nature Communications · Feb 3, 2021Peer-reviewedGenetics