Mediation Analysis with Compositional Exposures
Jing Ma, Poorbita Kundu, Timothy W. Randolph, Sandi L. Navarro, Meredith A.J. Hullar
The paper introduces a latent variable mediation framework to analyze the gut microbiome's indirect effects on clinical outcomes through compositional data structures.
bioRxiv · Sep 29, 2026 · PreprintBioinformatics