A Negative Feedback Regulates The Flow Of Signal Through Akt/mTORC1/S6K1 Pathway
Poulami Dutta, Vimalathithan Devaraj, Biplab Bose
The paper demonstrates that negative feedback in the Akt/mTORC1/S6K1 pathway filters phospho-Akt signals, leading to transient phospho-S6K1 activation and differential responses to insulin and IGF-1.
bioRxiv · Sep 3, 2017 · PreprintSystems Biology