Learning the shape of protein micro-environments with a holographic convolutional neural network
M. N. Pun, A. Ivanov, Q. Bellamy, Z. Montague, C. LaMont, P. Bradley, J. Otwinowski, A. Nourmohammad
This paper introduces H-CNN, a machine learning model that predicts mutation impacts on protein function using structural and evolutionary data.
bioRxiv · Oct 31, 2022 · PreprintBiophysics