Dynamics of cell type transition mediated by epigenetic modifications
Rongsheng Huang, Qiaojun Situ, Jinzhi Lei
This study presents a hybrid model of stem cell differentiation driven by epigenetic modifications, showing how random inheritance of epigenetic states can induce cell differentiation, dedifferentiation, and transdifferentiation.
Journal of Theoretical Biology · Nov 16, 2023Peer-reviewedSystems Biology