Author

R. Dutta Roy

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Biochemistry· 1

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Approach:statistical model· 1

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C. Rosenmund· 1 shared M. I. Stefan· 1 shared

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2015-2015 · peak 1/yr

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1 shared paperBiochemistry

C. Rosenmund

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Recent·Most cited

Cooperative Binding Mitigates the High-Dose HookEffect

R. Dutta Roy, C. Rosenmund, M. I. Stefan

This study mathematically models how allostery mitigates the high-dose hook effect using calmodulin as a case study, showing that increased allosteric activator concentrations can reduce protein activity.

bioRxiv · Jun 30, 2015Biochemistry