The blueprint of human functional architecture shifts from cognition to anatomy during perturbations of consciousness
Andrea I. Luppi, Dragana Manasova, Justine Y. Hansen, Zhen-Qi Liu, Asa Farahani, Yonatan Sanz Perl, Jakub Vohryzek, Daniel Golkowski, Andreas Ranft, R. Ilg, Denis Jordan, Vincent Luce Bonhomme, Audrey Vanhaudenhuyse, Athena Demertzi A, Océane Jaquet, , Bratislav Mišić
This study shows that cognitive co-activation dominates fMRI synchrony in the awake brain but is replaced by anatomical and molecular constraints during consciousness perturbations.
bioRxiv · Jun 10, 2026 · PreprintNeuroscience