Author

R. Kasmer

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Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

C. Atilgan· 1 shared F. Jalalypour· 1 shared M. Ilter· 1 shared N. Karakas· 1 shared O. Sensoy· 1 shared O. Topcu· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperCancer Biology

C. Atilgan

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1 paper

Recent·Most cited

Inhibition of mutant RAS-RAF interaction by mimicking structural and dynamic properties of phosphorylated RAS

M. Ilter, R. Kasmer, F. Jalalypour, C. Atilgan, O. Topcu, N. Karakas, O. Sensoy

The paper shows that small molecules can disrupt HRASG12D-RAF interaction by mimicking phosphorylation effects on Switch I, as validated by MD simulations and in vitro experiments.

bioRxiv · Apr 24, 2022Cancer Biology